Airway hyperresponsiveness in bronchial asthma: pathogenesis basics
نویسندگان
چکیده
منابع مشابه
Bronchial Hyperresponsiveness in Asthma*
Measurement ofnonspecific bronchial hyperresponsiveness remains largely a research tool in asthma, and its usefulness in the assessment and management of asthma is poorly defined. We StUdied the relationship of bronchial hyperresponsiveness to the clinical severity of asthma in 54 asthmatic subjects. In order to find out whether measurement of bronchial hyperresponsiveness could be used to pred...
متن کاملSpontaneous changes of airway hyperresponsiveness in bronchial asthma.
RACHIELE et al. [1) reported on stable asthmatics in whom two histamine inhalation tests were carried out on six different days at 8, 16 and 22 h. In seven out of fifteen asthmatic subjects significant diurnal rhythms with a time range of least excitability between 9.8 and 23.1 h could be demonstrated. Diurnal changes of airway responsiveness may, therefore, be important in some patients with b...
متن کاملAirway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma.
BACKGROUND There are few data in asthma relating airway physiology, inflammation and remodelling and the relative effects of inhaled corticosteroid (ICS) treatment on these parameters. A study of the relationships between spirometric indices, airway inflammation, airway remodelling, and bronchial hyperreactivity (BHR) before and after treatment with high dose inhaled fluticasone propionate (FP ...
متن کاملSmall Airway Impairment and Bronchial Hyperresponsiveness in Asthma Onset
PURPOSE Our study tried to find a relationship between baseline FEF25-75% and airway hyperresponsiveness (AHR) and whether a greater FEF25-75% impairment may be a marker of a more severe hyperresponsiveness in subjects with normal FEV1 and FEV1/FVC and suggestive asthma symptoms. Besides, we tried to asses a FEF25-75% cut-off value to identify hyper-reactive subjects. METHODS 4,172 subjects (...
متن کاملBronchial hyperresponsiveness in the assessment of asthma control: Airway hyperresponsiveness in asthma: its measurement and clinical significance.
The two key pathophysiologic features of asthma are bronchial hyperresponsiveness (BHR) and airway inflammation. Symptoms and lung function are the most accessible clinical markers for the diagnosis of asthma as well as for assessing asthma control using the most effective treatment of asthma, inhaled corticosteroids (ICS). However, BHR and inflammation usually take longer to resolve using ICS ...
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ژورنال
عنوان ژورنال: Bulletin of Siberian Medicine
سال: 2002
ISSN: 1819-3684,1682-0363
DOI: 10.20538/1682-0363-2002-4-65-74